- Florida club: 49 killed -
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   A heavily-armed gunman opens fire inside a gay nightclub in the city of Orlando on June 12, 2016 and kills 49 people.
   The attacker is killed in a shootout with police; he pledges allegiance to the Islamic State group, which later claims responsibility.

   - Virginia Tech: 32 killed -
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   A 23-year-old student of Korean origin goes on a rampage at Virginia Tech University in the town of Blacksburg in April 2007. He kills 27 students and five teachers before committing suicide.

   - Sandy Hook: 26 killed -
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   A disturbed 20-year-old man kills his mother in Newtown, Connecticut, in December 2012 before blasting his way into Sandy Hook Elementary School and shooting dead 20 six- and seven-year old children and six adults. He commits suicide.
  
   - Texas restaurant: 22 dead -
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   In October 1991 a man shoots dead 22 people in a restaurant in the town of Killeen and then kills himself.
  
   - California office party: 14 dead -
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   A newlywed radicalized Muslim couple storm an Christmas office party at a social services center in San Bernardino in December 2015 and gun down 14 people, wounding 22 others. They are shot dead by police.

   - Fort Hood military base: 13 dead -
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   In November 2009 a US army psychiatrist opens fire at his military base in Killeen, killing 13 people and wounding 42, before being overpowered by police. 

   - New York immigrant center: 13 dead -
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   A Vietnamese immigrant shoots dead 13 people at a civic center in the New York state city of Binghamton in April 2009, before killing himself.

   - Marines: 12 dead -
   ====================
  
   A troubled former serviceman shoots randomly at workers at the Washington Navy Yard headquarters in September 2013, killing 12 people before he is shot dead by officers.

   - Denver cinema: 12 dead -
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   A young man wearing body armor storms a cinema showing a late-night premiere of a Batman film in Aurora in July 2012, opening fire and releasing tear gas. Twelve people and 70 wounded. He is sentenced to life in prison.

   - Columbine High: 12 dead -
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   Two teenage boys shoot and kill 12 classmates and a teacher at Columbine High School in Littleton, Colorado, in April 1999, before killing themselves.